ARCHE partner, the University of Bordeaux, received a delivery of a new high resolution mass spectrometer, which will be entirely dedicated to cultural heritage analysis. The instrument is an Orbitrap Eclipse equipped with collision-induced dissociation (CID), higher-energy collisional dissociation (HCD), electron-transfer dissociation (ETD) (+ electron-transfer higher energy collision dissociation, EThcD; electron transfer collision-induced dissociation, ETciD) and ultraviolet photodissociation (UVPD), available at any stage of MSn with detection in the Orbitrap mass analyzer or linear ion trap analyzer. The instrument is also equipped with high-field asymmetric-waveform ion mobility spectrometry (FAIMS), high mass range with MSⁿ (HMRⁿ, proton transfer charge reduction (PTCR). The orbitrap Eclipse is coupled with a Vanquish Neo system (0,001 to 100 uL/min at 1500 bar max).