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Francesca Galluzzi performed HDX-MS analysis on paint mock-ups to study the confirmational changes of paints due to interactions with inorganic pigments. This research was performed as part of her PhD in the EU Marie Skłodowska-Curie ETN TEMPERA, and a postdoctoral fellowship granted by the University of Bordeaux and IdEX, with the support of CNRS and the Nouvelle-Aquitaine Region (France).